{"id":44796,"date":"2020-10-05T05:00:00","date_gmt":"2020-10-05T13:00:00","guid":{"rendered":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/2020\/10\/05\/terpinolene-the-powerful-medicinal-terpene-with-anti-cancer-promise\/"},"modified":"2020-10-05T13:45:21","modified_gmt":"2020-10-05T21:45:21","slug":"terpinolene-the-powerful-medicinal-terpene-with-anti-cancer-promise","status":"publish","type":"post","link":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/2020\/10\/05\/terpinolene-the-powerful-medicinal-terpene-with-anti-cancer-promise\/","title":{"rendered":"Terpinolene: The Powerful Medicinal Terpene with Anti-Cancer Promise"},"content":{"rendered":"<\/p>\n<p>Few cannabis consumers are fully aware of the complex molecular chemistry of the herb they vaporize, smoke, or eat. <\/p>\n<p>Terpenes like terpinolene are the aromatic molecules responsible for the sometimes revealingly pungent aroma of many strains of cannabis. Although the chief purpose of this family of chemicals is an evolutionary defense mechanism against pests and predators, terpenes have been found to deliver medicinal efficacy that equals that of cannabinoids such as <a href=\"\/how-to-understand-cbd-lingo\/\">CBD<\/a> and <a href=\"\/what-is-thc\/\">THC<\/a>.<\/p>\n<p>More than 20,000\u00a0<a href=\"\/?s=terpenes\">terpenes<\/a>\u00a0exist throughout nature, about 200 of which have been identified in various strains of cannabis. Terpinolene (sometimes denoted as \u201cTPO\u201d) is considered a minor, or secondary, terpene and features an aroma resembling sweet pine. \u00a0It delivers a taste reminiscent of citrus and is produced in many plants in nature other than cannabis, including allspice, cumin, junipers, parsnip, rosemary, sage, and tea tree.<\/p>\n<h4><strong>The Details of\u00a0Terpinolene<\/strong><\/h4>\n<p>In terms of medicinal efficacy, terpinolene kills cancer cells and acts as a sedative. In addition, it displays antibacterial properties and is both an anti-fungal and an anti-oxidant. It is employed as a flavoring agent by various segments of the food industry. It is also used to manufacture plastics and resins and is an effective repellent against pests such as mosquitoes and weevils.<\/p>\n<p>A\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24084350\" target=\"_blank\" aria-label=\"undefined (opens in a new tab)\" rel=\"noreferrer noopener\">2013 study<\/a>\u00a0found this special molecule to be a powerful anti-cancer agent. Concluded the study\u2019s researchers, \u201cOur findings clearly demonstrate that terpinolene is a potent antiproliferative agent for brain tumour cells and may have potential as an anticancer agent, which needs to be further studied.\u201d<\/p>\n<h4><strong>The Research<\/strong><\/h4>\n<p>A\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24084350\" target=\"_blank\" aria-label=\"undefined (opens in a new tab)\" rel=\"noreferrer noopener\">2013 study<\/a>\u00a0entitled \u201cAnticancer and Antioxidant Properties of Terpinolene\u201d that was published in the journal Arh Hig Rada Toksikol found terpinolene to be a \u201cpotent antiproliferative agent for brain tumour cells\u201d and surmised that this powerfully medicinal terpene \u201cmay have potential as an anticancer agent,\u201d an issue in obvious need of further research due to the 91 million people worldwide who suffer more than 100 types of cancers.<\/p>\n<p>The researchers concluded, \u201cOur findings clearly demonstrate that terpinolene is a potent antiproliferative agent for brain tumor cells and may have potential as an anticancer agent, which needs to be further studied.\u201d<\/p>\n<p>A\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22740904\" target=\"_blank\" aria-label=\"undefined (opens in a new tab)\" rel=\"noreferrer noopener\">2012 study<\/a>\u00a0entitled \u201cTerpinolene, a Component of Herbal Sage, Downregulates AKT1 Expression in K562 Cells\u201d and published in the journal Oncology Letters found the terpene terpinolene to be an effective agent in the battle against a variety of cancers.<\/p>\n<p>Concluded the study\u2019s researchers, \u201cIncreased expression and\/or activation of AKT is involved in a variety of human cancers. In cells treated with sage or rosemary extract, mRNA and protein expression levels of AKT1 were reduced compared with those of the control cells 48 hours after the herbal treatments. We found that terpinolene, a common component of sage and rosemary, markedly reduced the protein expression of AKT1 in K562 cells and inhibited cell proliferation.\u201d<\/p>\n<p><em>Originally published on <a aria-label=\"undefined (opens in a new tab)\" href=\"https:\/\/cannabisaficionado.com\/terpinolene-the-powerful-medicinal-terpene-that-battles-cancer\/\" target=\"_blank\" rel=\"noreferrer noopener\">cannabisaficionado.com<\/a>.<\/em><\/p>\n<p><strong>TELL US<\/strong>, how well do you know your terpenes?<\/p>\n<p>The post <a rel=\"nofollow\" href=\"https:\/\/cannabisnow.com\/terpinolene-the-powerful-medicinal-terpene-with-anti-cancer-promise\/\">Terpinolene: The Powerful Medicinal Terpene with Anti-Cancer Promise<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/cannabisnow.com\">Cannabis Now<\/a>.<\/p>\n<p>&#013;<br \/>\n&#013;<br \/>\nRead More: <a href=\"https:\/\/cannabisnow.com\/terpinolene-the-powerful-medicinal-terpene-with-anti-cancer-promise\/\" target=\"_blank\" rel=\"noopener noreferrer\">Terpinolene: The Powerful Medicinal Terpene with Anti-Cancer Promise<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Few cannabis consumers are fully aware of the complex molecular chemistry of the herb they vaporize, smoke, or eat. Terpenes like terpinolene are the aromatic molecules responsible for the sometimes revealingly pungent aroma of many strains of cannabis. Although the chief purpose of this family of chemicals is an evolutionary<span class=\"more-link\"><a href=\"https:\/\/cannabiscultivatornews.com\/home\/index.php\/2020\/10\/05\/terpinolene-the-powerful-medicinal-terpene-with-anti-cancer-promise\/\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":434,"featured_media":0,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1140,50,536,187,1598,5998],"tags":[],"_links":{"self":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/44796"}],"collection":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/users\/434"}],"replies":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/comments?post=44796"}],"version-history":[{"count":1,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/44796\/revisions"}],"predecessor-version":[{"id":44797,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/44796\/revisions\/44797"}],"wp:attachment":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/media?parent=44796"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/categories?post=44796"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/tags?post=44796"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}