{"id":37988,"date":"2019-09-09T05:00:35","date_gmt":"2019-09-09T13:00:35","guid":{"rendered":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/2019\/09\/09\/will-cbd-be-an-answer-to-antibiotic-resistant-superbugs\/"},"modified":"2019-09-09T12:50:33","modified_gmt":"2019-09-09T20:50:33","slug":"will-cbd-be-an-answer-to-antibiotic-resistant-superbugs","status":"publish","type":"post","link":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/2019\/09\/09\/will-cbd-be-an-answer-to-antibiotic-resistant-superbugs\/","title":{"rendered":"Will CBD Be an Answer to Antibiotic-Resistant Superbugs?"},"content":{"rendered":"<\/p>\n<p>Amid all the utopian sensationalism about the supposedly salubrious properties of the cannabinoid CBD, some are developing a skeptical attitude toward the newest amazing claims. But the latest is among the most ambitious we\u2019ve heard yet.<\/p>\n<p>On Aug. 28, new research <a rel=\"noreferrer noopener\" href=\"https:\/\/www.frontiersin.org\/journals\/cellular-and-infection-microbiology\/sections\/molecular-bacterial-pathogenesis#about\" target=\"_blank\">was published<\/a> that suggests CBD can help antibiotics fight antibiotic-resistant bacteria. The research, conducted by a team of scientists based in the United Kingdom and published in the peer-reviewed journal <em>Frontiers in Cellular and Infection Microbiology<\/em>, examined a strain of E. coli bacteria and its release of \u201cmembrane vesicles,\u201d which bacteria use to communicate and spread. The researchers found that CBD enhanced an antibiotic\u2019s ability to stop the release of those membrane vesicles. <\/p>\n<p>\u201cCBD<br \/>\nmay pose as a putative adjuvant agent for tailored co-application with selected<br \/>\nantibiotics,\u201d the researchers concluded. Or, in regular speak: CBD can help<br \/>\nantibiotics fight specific bacteria better. They continued that, therefore, CBD<br \/>\nmay \u201chelp reduce antibiotic resistance.\u201d<\/p>\n<p>This study reinforces a recent discovery from Australian researchers that found CBD killed all strains of bacteria they tested in a laboratory \u2014 including some that have developed resistance to existing antibiotics. Even more encouragingly, the bacteria did not develop resistance to CBD after being exposed to it for 20 days. They concluded that CBD may be able to outmaneuver <a href=\"https:\/\/www.statnews.com\/2016\/07\/26\/superbug-antibiotics-bacteria\/\" target=\"_blank\" rel=\"noreferrer noopener\">the entire process by which superbugs develop<\/a>.<\/p>\n<p>Mark Blaskovich, team leader from the University of Queensland\u2019s Institute for Molecular Bioscience, admitted to\u00a0<a href=\"https:\/\/www.newsweek.com\/cannabis-ingredient-cbd-antibiotic-1445169\" target=\"_blank\" rel=\"noreferrer noopener\">Newsweek<\/a>,\u00a0\u201cWe still don\u2019t know how it works\u2026 [I]t may have a unique mechanism of action given [that] it works against bacteria that have become resistant to other antibiotics, but we still don\u2019t know how.\u201d<\/p>\n<p>The\u00a0<a href=\"\/look-out-cbd-could-soon-be-used-as-an-antibiotic\/\">findings were presented<\/a>\u00a0at the\u00a0American Society for Microbiology\u2019s\u00a0Microbe 2019\u00a0conference in San Francisco in June. The findings have not yet been published in a peer-reviewed journal.\u00a0\u00a0<\/p>\n<p>So<br \/>\nthe research, as promising as it seems, is in the early stages. When asked for<br \/>\nhis advice for those who might ditch standard antibiotics for cannabis-based<br \/>\nhome remedies, Blaskovich responded unequivocally: \u201cDon\u2019t! Most of what we<br \/>\nhave shown has been done in test tubes \u2014 it needs a lot more work to show it<br \/>\nwould be useful to treat infections in humans.\u201d<\/p>\n<p>At<br \/>\nthis stage, \u201cit would be very dangerous to try to treat a serious<br \/>\ninfection with cannabidiol instead of one of the tried and tested<br \/>\nantibiotics,\u201d he stressed.<\/p>\n<h4><strong>Medical Establishment Paying Attention\u00a0\u00a0<\/strong><\/h4>\n<p>The<br \/>\nAustralian study has won interest from the medical establishment, with a flurry<br \/>\nof coverage in both popular and trade journals since the San Francisco<br \/>\nunveiling in June. \u00a0<\/p>\n<p>CBD<br \/>\nwas found to disrupt biofilm, the layer of liquid around bacteria cells that<br \/>\nmakes it difficult for antibiotics to penetrate and kill. Results showed that<br \/>\n\u201cCBD is much less likely to cause resistance than the existing<br \/>\nantibiotics,\u201d Blaskovich said.\u00a0\u00a0<\/p>\n<p>The researchers looked at how effective CBD was compared to common antibiotics, such as vancomycin (marketed as\u00a0<a href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-9593-7154\/vancocin-oral\/vancomycin-solution-oral\/details\" target=\"_blank\" rel=\"noreferrer noopener\">Vancocin<\/a>) and daptomycin \u2014 to very positive results. <\/p>\n<p>In<br \/>\nthe Australian study, the researchers also unfortunately found the CBD to be<br \/>\neffective against Gram-positive bacteria but not Gram-negative. Gram-positive<br \/>\nstrains cause serious skin infections and pneumonia, among other conditions.<br \/>\nGram-negative types include salmonella and E. coli, more associated with<br \/>\ngastrointestinal disorders.<\/p>\n<p>Among the stateside companies enthused by the antimicrobial potential of CBD is\u00a0<a rel=\"noreferrer noopener\" href=\"https:\/\/ecogenlabs.com\/\" target=\"_blank\">EcoGen Laboratories<\/a>\u00a0of Grand Junction, Colorado. With 160,000 square feet of greenhouse cultivation, EcoGen is a major source of the CBD isolate and distillate found in products available in retail outlets nationwide. It is also providing isolate, distillate and plant samples to researchers at UCLA and other universities.<\/p>\n<p>EcoGen<br \/>\nchief growth officer Derek Du Chesne told Cannabis Now that he hopes that the<br \/>\npromising claims of the Australian study will help break down the barriers to<br \/>\nresearch in the United States. <\/p>\n<p>\u201cWe<br \/>\nwould love to supply them cannabinoids and material they will need to develop<br \/>\nCBD antibiotics,\u201d he says.<\/p>\n<p>Du<br \/>\nChesne rattled off various established applications of CBD \u2014 for instance, he<br \/>\nsays it is already being used in dental offices as a supplemental<br \/>\nanti-inflammatory treatment. But he also urges research into the<br \/>\npharmacological value of the \u201clesser known cannabinoids.\u201d\u00a0<\/p>\n<p>He mentions cannabicyclol (CBL), <a href=\"\/cbg\/\">cannabigerol<\/a> (CBG), cannabichromene (CBC) and <a href=\"\/cbn-inside-cannabinoid-relieves-insomnia\/\">cannabinol<\/a> (CBN) as holding possibilities for similar breakthroughs.<\/p>\n<p>Du Chesne calls CBG the \u201c<a href=\"\/breeding-for-cannabinoids-the-cbg-seed\/\">next one in the spotlight<\/a>\u201d for its anti-inflammatory value. CBN research shows potential for cancer-fighting, sleep-aiding and anti-seizure applications. Du Chesne acknowledges that CBN is difficult to extract, and is only found in trace amounts in the plant. \u201cBut extraction technology is improving,\u201d he says.\u00a0<\/p>\n<p>A<br \/>\nfreer legal environment also helps to make extraction of such cannabinoids more<br \/>\nviable: \u201cFour years ago, CBD isolate went for $20,000 a kilo. Now it\u2019s<br \/>\n$2,000 a kilo due to the supply chain being freed up by the Farm Bill.\u201d<br \/>\nCBG now goes for $30,000 a kilo, half what it was last year.<\/p>\n<p>\u201cThere\u2019s<br \/>\nbeen a lot more money put toward suppressing the research than toward the<br \/>\nresearch,\u201d Du Chesne notes. \u201cThe science hasn\u2019t caught up with the<br \/>\nmarket, Now that the raw material is available and the restrictions on the<br \/>\nresearch are going down, it is going to affect the pharmaceutical business in a<br \/>\nvery large-scale way.\u201d<\/p>\n<p><strong>TELL US,<\/strong> are you afraid of<br \/>\nantibiotic-resistant \u201csuperbugs\u201d?<\/p>\n<p>The post <a rel=\"nofollow\" href=\"https:\/\/cannabisnow.com\/will-cbd-be-an-answer-to-antibiotic-resistant-superbugs\/\">Will CBD Be an Answer to Antibiotic-Resistant Superbugs?<\/a> appeared first on <a rel=\"nofollow\" href=\"https:\/\/cannabisnow.com\">Cannabis Now<\/a>.<\/p>\n<p>&#013;<br \/>\n&#013;<br \/>\nRead More: <a href=\"https:\/\/cannabisnow.com\/will-cbd-be-an-answer-to-antibiotic-resistant-superbugs\/\" target=\"_blank\">Will CBD Be an Answer to Antibiotic-Resistant Superbugs?<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Amid all the utopian sensationalism about the supposedly salubrious properties of the cannabinoid CBD, some are developing a skeptical attitude toward the newest amazing claims. But the latest is among the most ambitious we\u2019ve heard yet. On Aug. 28, new research was published that suggests CBD can help antibiotics fight<span class=\"more-link\"><a href=\"https:\/\/cannabiscultivatornews.com\/home\/index.php\/2019\/09\/09\/will-cbd-be-an-answer-to-antibiotic-resistant-superbugs\/\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":190,"featured_media":0,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10480,50,136,53,415],"tags":[],"_links":{"self":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/37988"}],"collection":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/users\/190"}],"replies":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/comments?post=37988"}],"version-history":[{"count":1,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/37988\/revisions"}],"predecessor-version":[{"id":37989,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/37988\/revisions\/37989"}],"wp:attachment":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/media?parent=37988"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/categories?post=37988"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/tags?post=37988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}