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M<\/span>ara Gordon and Stewart Smith\u2019s two dogs are the dominating force of their home. When our group of cannabis-savvy women arrive and jump out of the car \u2014 already savoring deep breaths of the fresh salt air blowing off of Bodega Bay \u2014 the couple has not yet returned home from a trip to Los Angeles.<\/p>\n We are welcomed inside by Aunt Zelda\u2019s research and development coordinator, Justin Kander, and a flurry of activity as a hyper-charged pup circles round and round the space.<\/p>\n When Gordon and Smith arrive, the activity only increases as the smaller dog leaps from the ground into Gordon\u2019s arms.<\/p>\n \u201cThis evolved from the wolf, I mean think about that. You know?,\u201d she says, pointing to the dog. \u201cI mean if you think about hybrids and all that in our industry, this is a hybrid of a wolf.\u201d<\/p>\n I made the short drive from Berkeley to Bodega Bay with friends to speak with the founders of Aunt Zelda\u2019s<\/a> about cannabis\u2019 promise as a true medicine. I found their home to be tastefully decorated and was surprised to see that it bore only one small token of their business \u2014 which started as an edible<\/a> company \u2014 in the form of a marijuana cookie cutter in the kitchen.<\/p>\n While both Gordon and Smith boast an incredible knowledge of the curative applications of cannabis, it wasn\u2019t always that way. They each have extraordinary narratives of healing themselves with medical cannabis, but it was their path to discovery that has helped and will continue to help countless others find their own relief.<\/p>\n The Science of Medical Medical Marijuana<\/strong><\/p>\n \u201cThe question that we\u2019ve been seeking to solve for the last six plus years now is, \u2018Is there a way to accurately and consistently dose cannabinoids<\/a> and terpenes<\/a> over time across diseases?\u2019\u201d Gordon says, when she catches her breath and settles down to speak with us in the living room. \u201cWe set out to figure out what different criteria that we would have to address in order to be able to do this.\u201d<\/p>\n Founded in 2011, the business now has three distinct elements, all within a holding company called Caziwell: Aunt Zelda\u2019s<\/a>, a medical cannabis provider that creates infused olive oils, strain-specific extracts and cannabis topicals; Calla Spring Wellness<\/a>, a team of medical experts offering cannabis recommendations in California; and Zelda Therapeutics<\/a>, an international organization of cannabis experts focused on pre-clinical and clinical scientific research<\/p>\n All of Aunt Zelda\u2019s products are made in small batches and tested rigorously to bring an understanding of the cannabinoids (the chemical compounds like THC <\/a>and CBD<\/a> which interact with receptors throughout the body) and terpenes<\/a> (the aromas that give cannabis much of its effects) to patients so they can successfully heal.<\/p>\n \u201cMy background is as a process engineer so it\u2019s kind of a natural space for me to be looking for patterns, repeatability and consistency in a crazy world like cannabis,\u201d Gordon says.<\/p>\n While we are speaking with Gordon, Smith is taking calls from growers and reviewing a presentation he has given on different extraction methods. While extremely knowledgeable about cannabis himself, Gordon is the most public face of the company.<\/p>\n Finding the Right Dose When Gordon tried a cannabis edible for the first time, her initial reaction to the ensuing reprieve from long term pain, which had once confined her to a wheelchair, was anger.<\/p>\n \u201cMy immediate reaction was I was furious, that nobody had told me years before and that I had suffered all these years needlessly,\u201d she said. \u201cAnd then the second thing was, \u2018Why doesn\u2019t everybody know about this?\u2019 And then, \u2018How do you know what to do and how do you know what to get?\u2019\u201d<\/p>\n Gordon had stopped working because of health reasons in 2003 and her husband was also experiencing extreme pain stemming from a pole vaulting accident in high school that broke his back.<\/p>\n When Smith \u2014\u00a0sober for nearly 30 years \u2014\u00a0had to have a back surgery in 2007, he was not willing to take a gamble on becoming addicted to opioids<\/a>. Searching for solutions, the couple turned to a friend they had met while living on the road for two years in a teardrop trailer, now located in their beachside backyard.<\/p>\n \u201cTalk about a different lifestyle, I mean I\u2019m so straight,\u201d Gordon says of her friend. \u201cShe was one of these wake and bake people \u2014\u00a0that\u2019s what she called herself. I had never heard of any of this terminology at all. I\u2019d never heard of \u2018wake and bake,\u2019 I\u2019d never heard of \u2018puff, puff, pass.\u2019 All these things I learned from her.\u201d<\/p>\n Once she tried a brownie her friend gave her and felt her pain decrease \u201cfrom an eight-and-a-half to a two,\u201d Gordon and Smith both got their medical marijuana recommendations and went to a dispensary recommended by their doctor.<\/p>\n Gordon remembers their first purchase: caramel corn, a brownie and a marshmallow rice square wrapped in cellophane with an adhesive tape label marked in permanent ink that read \u201cfive to 20 doses.\u201d<\/p>\n \u201cMe being me, I immediately took out a new Moleskine [notebook],\u201d she says describing the effort she took to weigh each piece and note the duration and effects of the medicine. \u201cI did all this from the very first dose and it was insane.\u201d<\/p>\n The range of doses was wildly inconsistent, even changing depending on which piece of the edible they each consumed. Upon their first purchase at a medical marijuana dispensary, Gordon had some serious questions.<\/p>\n \u201cWhat\u2019s five to 20? What does that mean and what\u2019s a dose?\u201d<\/p>\n Aunt Zelda<\/strong>\u2019s Carrot Cake<\/strong><\/p>\n Discouraged by the inconstant results of dispensary-purchased edibles and knowing they couldn\u2019t afford the medicine they needed at such a high retail cost, Gordon and Smith set out to create edibles for themselves. And, because they did not know any growers in California, they traveled to Oregon and paid $500 each to become patients there.<\/p>\n They then purchased 2 ounces of Chemdawg and, with no instructions \u2014 Gordon says these days you can\u2019t \u201cswing a cat without hitting an expert\u201d \u2014 made an infused oil that \u201caccidentally\u201d came out right.<\/p>\n The baking gene runs deep in Gordon\u2019s family; her grandmother was a baker and her dad invented cheesecake on a stick in his \u201csecond to last career.\u201d It was while searching for a recipe heavy in oil that Gordon found her aunt Zelda\u2019s carrot cake.<\/p>\n \u201cI know how to make it so that the outside pieces are just the same moisture level as the middle,\u201d she boasts, adding that a common problem with edibles is dryness on the outer edges, which means if you eat one piece you might not feel it, but eat another and you might not be able to open your eyes.<\/p>\n The turning point for their business came when a friend of their attorney provided a profound piece of advice.<\/p>\n \u201cWhy are you building everyone a house when you can provide the lumber?\u201d Gordon says. \u201cIn other words, instead of baking everybody a cake, provide them with the infused oil because that\u2019s scalable.\u201d<\/p>\n Talking in Waiting Rooms<\/strong><\/p>\n Taking the edibles out of the business equation meant a true focus on the medical applications of cannabis. Edibles are not \u201cwhere it\u2019s at\u201d to treat diseases, Gordon explains, because one has to worry about things like added sugars and all the varying ways bioavailability is shifted with different methods of ingestion.<\/p>\n Take the oil, then eat a carrot cake or a salad \u2014 \u201cyour medicine is your medicine,\u201d she says.<\/p>\n Her voice drops when speaking of the first cancer patient Aunt Zelda\u2019s treated with careful doses of infused cannabis extract, saying that they did what they could without knowing all the things they do now.<\/p>\n \u201cYou know how it is, people talk in waiting rooms,\u201d she says.<\/p>\n Once word of the company\u2019s reputation got out, the family of a 6-year-old girl suffering from cancer requested extracts from Aunt Zelda\u2019s.<\/p>\n \u201cThis was really when our whole life flipped was because of that child, because Stewart took over making the oil,\u201d Gordon says. \u201cUp until that point I had been the only one making the oil \u2014\u00a0I had been doing all the patient care, doing everything.\u201d<\/p>\n The young girl, who has since died, was in dire straights and non-verbal as her parents shifted her from treatment to treatment. Even after arriving upon the potential hope of medical cannabis, the girl\u2019s mother still had concerns.<\/p>\n \u201cHer mother took the medicine herself and said \u2018I can\u2019t give this to my child, it got me so stoned.\u2019 And I\u2019m like, \u2018Do you have cancer? Do you take her chemo drugs too?\u2019 That always is just one of those things that just irks the heck out of me,\u201d Gordon said.<\/p>\n Caring for the Patients<\/strong><\/p>\n Aunt Zelda\u2019s is currently a direct-to-patient service that provides deliveries via a courier service. It is also in the process of expanding to dispensaries, and Gordon estimates they are currently treating around 3,400 individuals.<\/p>\n \u201cWe set titration schedules and what our target therapeutic doses are, and then in our feedback loop we find out if it\u2019s too little or too much,\u201d Gordon says. \u201cAnd the way that we do that is by looking at scans, bloodwork, pathology reports, tumor markers \u2014 whatever the marker or the mechanism of review would be for that particular diagnosis, we\u2019re able to track it.\u201d<\/p>\n The company has established 300 different data points for each patient to establish dosing protocols for specific diseases, including the 200 different types of flexion cancers.<\/p>\n \u201cWe\u2019ve also set up rules to backfill [patient data] based upon our experience and our research because it goes on more than just what people are using,\u201d Gordon says. \u201cI mean, we\u2019re working with the chief scientists around the world and some of the top researchers and medical professionals to understand more about the endocannabinoid system<\/a> and the way cannabinoids interact with different diseases.\u201d<\/p>\n Filling in the Gaps<\/strong><\/p>\n \u201cThis is bespoke medicine \u2014 there\u2019s no other way to think of it than bespoke,\u201d Gordon says. \u201cAll medicine is, but even this has certain extra complexity.\u201d<\/p>\n In saying that, she also reveals upcoming proposals to provide cannabis therapy, via her team of medical experts, for 10 diabetes patients from China in either California or Hawaii in the coming months.<\/p>\n \u201cI want to have a place where people can come and get set on which medicines work best for them, to get them titrated to a therapeutic dose and then send them on their way with a correct profile so that it\u2019s repeatable and sustainable,\u201d she says.<\/p>\n Both Gordon and Smith are committed to cannabis as a medicine and demonstrate an endless fascination with discovering more about the plant. Their day-to-day lives are filled with talk of scientific discoveries and new treatment methods for cannabis.<\/p>\n \u201cI was a primary caregiver for so many people. My mother, my father, my first husband, my sister, my brother in law, my best friend \u2014 so I\u2019ve done this a lot of times, besides myself,\u201d Gordon says. \u201cI had to learn how to receive after giving, giving, giving, but I know<\/em> where the holes are and hopefully we\u2019re filling those.\u201d<\/p>\n Originally published in Issue 26<\/a> of Cannabis Now.<\/em> LEARN MORE<\/strong><\/a><\/p>\n TELL US, <\/strong>do you use cannabis for medical purposes?<\/p>\n The post Aunt Zelda\u2019s<\/a> appeared first on Cannabis Now<\/a>.<\/p>\n
How a family recipe launched a company devoted to the promise of cannabis\u2019 ability to treat diseases. Mara Gordon and Stewart Smith\u2019s two dogs are the dominating force of their home. When our group of cannabis-savvy women arrive and jump out of the car \u2014 already savoring deep breaths ofContinue Reading<\/a><\/span><\/p>\n","protected":false},"author":46,"featured_media":18026,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[865,50,85,351,53],"tags":[],"_links":{"self":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/18025"}],"collection":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/users\/46"}],"replies":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/comments?post=18025"}],"version-history":[{"count":1,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/18025\/revisions"}],"predecessor-version":[{"id":18027,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/posts\/18025\/revisions\/18027"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/media\/18026"}],"wp:attachment":[{"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/media?parent=18025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/categories?post=18025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cannabiscultivatornews.com\/home\/index.php\/wp-json\/wp\/v2\/tags?post=18025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"http:\/\/cannabiscultivatornews.com\/home\/wp-content\/uploads\/2017\/07\/maragordon@2x-1024x661.jpg\")
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Each patient is provided specific dosing regimens to work with. The cost of the medicine ranges from between $50 for chronic pain to around $800 and $1,800 per month for cancer<\/a> medications.<\/p>\n
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\nRead More: Aunt Zelda\u2019s<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"